Mehr Details zu Publikationen sind auf peterhuylab.de verfügbar.

Covergraphiken

Unabhängige Karriere

2020

25. C. Kohlmeyer, S. Schäfer,* P. H. Huy,* G. Hilt,* "Formamide-Catalyzed Nucleophilic Substitutions: Mechanistic Insight and Rationalization of Catalytic Activity", ACS Catalysis   2020, 10, 11567-11577.

24. B. Zoller, T. Stach, P. H. Huy,* "Lewis Base Catalysis Enables the Activation of Alcohols bymeans of Chloroformates as Phosgene Substitutes", ChemCatChem  2020, 12, 5637–5643.

23. B. Zoller, J. Zapp, P. H. Huy,* "Rapid Organocatalytic Formation of Carbon Monoxide: Application towards Carbonylative Cross Couplings", Chem. Eur. J.  2020226, 9632-9638.

22. P. H. Huy, “Radikale durch Licht – molekularer Baukasten für komplexe Moleküle",Nachr. Chem.  202068(1), 80-84 (review, doi: 10.1002/nadc.20204089927). An English translation entitled "Light Promoted Radical Formation – Toolbox for the Construction of Complex Molecules" can be found on peterhuylab.de.

21. P. H. Huy, "Lewis Base Catalysis Promoted Nucleophilic Substitutions - Recent Advances and Future Directions", Eur. J. Org. Chem.  2020, 10-27 (review, Cover Feature).

2019

20. P. H. Huy,* P. Grewelinger, “Nicht essen, nur schauen – polyhalogenierte Naturstoffe aus Algen“, Nachr. Chem.  201967(9), 63-67 (review). English translation entitled "Beautiful but Toxic – Polyhalogenated Natural Products from Algae" available.

19. P. Huy, C. Czekelius in Science of Synthesis Knowledge Updates (Eds. H.-U. Reissig, E. Schaumann), Thieme Stuttgart,  2019, Vol. 2, “Chapter 32.4.4: Chloro, Bromo and Iodoalkanes”, 91-241 (review).

18. P. H. Huy,* C. Mbouhom, “Formamide Catalyzed Activation of Carboxylic Acids: Versatile and Cost-Efficient Amidation and Esterification“, Chem. Sci.  2019,10, 7399-7406 (doi: 10.1039/C9SC02126D).

17. P. H. Huy,* B. Zoller, "Blickpunkt Synthese - Bor-Lewis-Säurekatalyse: Amide atomeffizient synthetisieren“, Nachr. Chem.  2019, 67(5), 51-54 (review, English Translation available: "Boron Lewis Acid Catalysis: How to Synthesize Amides Atom-Efficiently").

16. P. H. Huy, “Formamide Catalysis Facilitates the Transformation of Aldehydes into Geminal Dichlorides”, Synthesis  2019, 51, 2474–2483.

2018

15. S. Motsch, C. Schütz, P. H. Huy,* “Systematic Evaluation of Sulfoxides as Catalysts in Nucleophilic Substitutions of Alcohols“, Eur. J. Org. Chem.  2018, 4541-4547.

14. T. Stach, J. Dräger, P. H. Huy,* „Nucleophilic Substitutions of Alcohols in High Catalytic Efficiency“, Org. Lett.  2018,20, 2980-2983.

13. P. H. Huy,* I. Filbrich, „A General Catalytic Method for Nucleophilic Substitutions in High Cost- and Atom-Efficiency“, Chem. Eur. J.  2018, 24, 7410–7416.

2016

12. P. H. Huy,* T. Hauch, I. Filbrich, "Lewis Base Catalyzed Nucleophilic Substitutions of Alcohols”, Synlett  2016, 27, 2631-2636.

11. P. H. Huy,* S. Motsch, S. M. Kappler, "Formamide als Lewis-Basen-Katalysatoren inSN-Reaktionen: Effiziente Transformationen von Alkoholen zu  Chloriden, Aminen und Ethern“, Angew. Chem.  2016, 128, 10300-10304; “Formamides as Lewis Base Catalysts inSN-Reactions - Efficient Transformation of Alcohols into Chlorides, Amines and Ethers”, Angew. Chem. Int. Ed.  2016, 55, 10145-10149.

10. P. H. Huy, I. Filbrich (Saarland University), “Method of converting alcohol to halide”, LU patent  2017/93108 (Priority date 2016, June 16th).

9. P. H. Huy (Saarland University), “Method of converting alcohol to halide”, WO patent  2016/202894 A1 (Priority date 2015, June 17st).

Postdoktorate und Doktorarbeit

2010-2015

8. R. Opitz, M. Müller, C. Reuter, M. Barone, A. Soicke, Y. Roske, K. Piotukh, P. Huy, M. Beerbaum, B. Wiesner, M. Beyermann, P. Schmieder, C. Freund, R. Volkmer, H. Oschkinat, H.-G. Schmalz,* R. Kühne,* "A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions“, Proc. Natl. Acad. Sci. USA  2015, 112, 5011-5016 .

7. P. H. Huy,* J. Westphal, A. M. P. Koskinen,* "Concise, stereodivergent and highly stereoselective synthesis of cis- and trans-2-substituted 3-hydroxypiperidines – development of a phosphite-driven cyclodehydration”, Beilstein J. Org. Chem.  2014, 10, 369-383.

6. P. H. Huy,* A. M. P. Koskinen,* "Efficient, Stereodivergent Access to 3-Piperidinols by traceless P(OEt)3-Cyclodehydration”, Org. Lett.  2013, 15, 5178-5181.

5. R. Kühne, H. Oschkinat, R. Opitz, M. Müller, H.-G. Schmalz, C. Reuter, P. Huy, "Structural mimetics of proline-rich peptides and use of the same“, WO patent 2013/030111 A1.

4. C. Reuter, P. Huy, J.-M. Neudörfel, R. Kühne, H.-G. Schmalz,* "Exercises in Pyrrolidine Chemistry: Gram Scale Synthesis of a Pro-Pro Dipeptide Mimetic with a Polyproline Type II Helix Conformation“, Chem. Eur. J.  2011, 17, 12037-12044.

3. P. Huy, H.-G. Schmalz,* “Practical One-pot Double Functionalizations of Proline”, Synthesis  2011, 954-960.

2. P. Huy, J.-M. Neudörfl, H.-G. Schmalz,* "A Practical Synthesis of trans-3-substituted Proline Derivatives through 1,4-Addition”, Org. Lett.  2011, 13, 216-219.

1. J. Zaminer, C. Brockmann, P. Huy, R. Opitz, C. Reuter, M. Beyermann, C. Freund, M. Müller, H. Oschkinat, R. Kühne,* H.-G. Schmalz,* „Adressierung von Protein-Protein-Wechselwirkungen durch niedermolekulare Verbindungen: ein Pro-Pro-Dipeptid-mimetikum mit PPII-Helixkonformation als Modul für die Synthese PRD-bindender LigandenAngew. Chem.  2010, 122, 7265–7269; “Addressing Protein–Protein Interactions with Small Molecules: A Pro-Pro Dipeptide Mimic with a PPII Helix Conformation as a Module for the Synthesis of PRD-Binding Ligands“, Angew. Chem. Int. Ed.  2010, 49, 7111–7115.